Nonwoven nanofibre membrane with IMAC technology

High concentration of special metal-based groups for Immobilized Metal ion Affinity Chromatography (IMAC). Tiss®-IMAC membranes allow histidine-tagged biomolecules to be specifically retained. Elution of the protein of interest can be carried out by changing the pH, or adding a competitive molecule, such as imidazole.



  • New format for IMAC technology based materials. Membrane made of nanofibers easier to use than traditional gels or particles suspensions.
  • Reusable and easy to regenerate.
  • Versatile. Purify proteins using native and denaturalization conditions.
  • Available with different metals attached for the purification of a broad variety of His-tagged proteins: Co, Ni, Cu and Fe.
  • Highly specific. No retention of undesired substances.
  • One step purification.
  • Minimal metal leaching.


Purification of recombinant Histidine- tagged proteins.

Competitive edge

The nanostructured nature of Tiss®-IMAC membranes allows to take advantage of a very high specific surface area thus enhancing the retention capacity of these membranes. Moreover, NanoMyP® is the only company that provides this type of membranes as they are based on an exclusive technology developed by the company.

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