Nonwoven nanofibre membrane for covalent immobilisation of biomolecules

Tiss®-Biosens is a nonwoven nanofibre membrane made by co-electrospinning. It has a pre-activated surface (containing 3-atom spacer) for direct covalent immobilisation of biomolecules and an internal core containing an oxygen-sensitive dye for optical oxygen transduction.

nonwoven, diagnostic



Our revolutionary technology has allowed the development of coaxial fibre tissues that contain two functionalities:

  1. They allow the direct and covalent attachment of any biomolecule under mild conditions of temperature and pH (RT and physiological pH) in a short period of time;
  2. They contain an oxygen indicator dye which allows the monitorization of reactions in which oxygen is produced or consumed.

This patented technology has the following features:

  • Do not need to be pre-activated for the immobilisation of biomolecules.
  • Covalent attachment of thiol-, amine- and/or imidazole- containing biomolecules to the surface of the membrane, resulting in a highly bio-active material.
  • Enhancing sensitivity with a lesser amount of the biomolecule.
  • Enhancing stability.
  • An absence of undesired interactions with a remarkably decreasing of the background after blocking.
  • Simple and rapid monitoring of reaction in which the oxygen is envolved (optical oxygen transduction)


Tiss®-Biosens is specially recommended to act as a support for all the applications that require the monitoring of a biochemical reaction in which the oxygen is envolved:

  • biosensors
  • the monitoring of enzymatic reaction of oxidase and peroxidase enzymes
  • incorporation of biosensors in microfluidic systems. 

Competitive edge

Tiss®-Biosens does not need to be pre-activated for immobilisation of biomolecules.

NanoMyP® is the only company that provides this type of membranes as they are based on a patented technology.

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“A microfluidic device with integrated coaxial nanofibre membranes for optical determination of glucose”. Sensors and Actuators B 250 (2017)

“A multifunctional material based on co-electrospinning for developing biosensors with optical oxygen transduction”. Anal. Chim. Acta (2018)


Catalog Number



Product data sheet




16x11 cm

Technical data sheet


For large orders, please request quotation to our sales department (commercial@nanomyp.com).

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